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Organometallic Chemistry

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What Is Organometallic Chemistry and Synthesis?

Organometallic chemistry mainly studies various issues such as the chemical reaction and synthesis of substances containing M-C bonds (that is, metal organic compounds). Organometallic chemical synthesis occupies an important place in organic synthesis research because of its unique and interesting reactivity. In recent years, organometallic compounds as materials in optics, electronics, medicine, etc. have been widely used in various industrial fields. Typical examples of organometallic compounds are butyllithium, dimethylzinc, triethylaluminum and so on. They can react with hydrocarbons, carbon dioxide, olefins, etc., or act as catalysts for various reactions, thus standing out in the process of synthesizing increasingly complex and customized organic compounds. For example, the functionalization process of porphyrins can be efficiently achieved through organometallic synthesis, enabling chemists to obtain a wide range of highly refined and complex porphyrin structures.

Addition reaction of tert-butyllithium as a nucleophile with tetraphenylporphyrinAddition reaction of tert-butyllithium as a nucleophile with tetraphenylporphyrin [1]

What We Do in Metalorganic Synthesis

At Alfa Chemistry, combining powerful computational chemistry capabilities and automated synthesis platforms, we are proud to bring you efficient and cost-effective metalorganic synthesis services, from computational metalorganic chemistry to automated organic synthesis and monitoring.

  • Computational Chemistry for Organometallic Chemistry

Computational Chemistry for Organometallic Chemistry

The development of computational chemistry theory and technology has accelerated the research and progress of current metal-organic synthesis, and at the same time greatly reduced the synthesis cost of chemists. Building correct chemical models is essential for computational studies of chemical behavior, and Alfa Chemistry's chemists have this important capability, to name a few:

  • Metalorganic Synthesis and Monitoring

Since the reactions involve highly reactive organometallic compounds such as lithium aluminum hydride, lithium borohydride, diisobutylaluminum hydride, and Grignard reagents, organometallic synthesis usually requires low temperature conditions. Relying on the advanced automated synthesis platform, Alfa Chemistry can efficiently handle metal-organic synthesis reactions under strict temperature control conditions and improve experimental safety. In addition, monitoring the process of organometallic chemistry and synthesis, exploring the reaction mechanism and kinetics is also an important part. Our analysis and detection tools cover FTIR spectroscopy, Raman spectroscopy, automated online sampling systems, etc.

Our service capabilities include but are not limited to:

  • Kinetics and mechanism of organometallic reaction
  • Structure determination of organometallic compounds
  • Metal-ligand bonding and ligand dissociation studies
  • Study on organometallic reactions in various solvents

Choose Alfa Chemistry

We use advanced automation tools and unrivaled expertise to quickly and efficiently perform metal-organic synthesis and explore the mysteries of metal-organic chemistry. At Alfa Chemistry, our goal is to provide our customers with the highest quality automated synthesis of organometallic chemistry. To get started with our services, or to discuss our capabilities with a member of our expert team, contact us today.

Reference

  • Satoru Hiroto, et al. Chem. Rev., 2017, 117, 4, 2910-3043.

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